We have always debated whether curcumin is best to take on an empty stomach or with meals. Taking with meals would appear to increase absorption since curcumin is fat soluble. Interestingly, this chart from Begum et al 2008 shows the contrary. One major question remains, however: can oral curcumin absorb into the human bloodstream at concentrations required to treat the diseases it is shown promise for in animal models?
Source: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2527621&rendertype=figure&id=F6
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